Description
Abhigra 100Mg Tablet
Sildenafil (ABHIGRA) 100 mg tablet is an inhibitor of the enzyme phosphodiesterase-5 (PDE5), which is primarily used to treat erectile dysfunction and pulmonary hypertension.
Sildenafil is a specific and potent inhibitor of cyclic guanosine monophosphate (cGMP) phosphodiesterase enzyme type 5 (PDE5) in the corpus cavernosum, which induces relaxation of pulmonary vascular smooth muscle cells. It complements reduced erectile capacity by increasing blood flow to the penis; Sildenafil also requires sexual stimulation to achieve its pharmacological effects.
Drug = Sildenafil
Strength = 100 mg
Manufacturer = Abhiflax
Quantity per case = 10 tablets (at the indicated price)
How to take Sildenafil (ABHIGRA) 100 mg tablet
This medicine can be taken with or without food. The tablet must be swallowed whole with a glass of water.
Try to take it at the same time every day. It must be taken regularly to be effective.
Take exactly as directed by your doctor or as directed on the label. Do not take more or less than your doctor has told you. Do not stop taking it unless directed by your doctor.
Sildenafil dose (ABHIGRA) 100 mg tablet
Adult: erectile dysfunction: 50 mg approximately 1 hour before sexual intercourse. Maximum dose of 100 mg / day.
Pulmonary arterial hypertension: 5 mg or 20 mg three times a day.
Missed dose of sildenafil (ABHIGRA) 100 mg tablet
If you often forget to take your medicine, tell your doctor and pharmacist.
Take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and return to the usual dosing schedule.
Under no circumstances do not double the dose.
Overdose
If you think you have taken Sildenafil more than the usual dose, seek medical help immediately.
Symptoms of overdose may include the following:
Hypotension
Syncope
Prolonged erection
Contraindication
People with the following health problems should not take Sildenafil:
Unstable angina
Heart failure
Loss of vision in 1 eye due to non-arteritic anterior ischemic optic neuropathy (naion)
Hypotension (BP <90/50 mmHg)
Recent history of stroke or myocardial infarction
Known hereditary degenerative disorders of the retina
Severe hepatic impairment
Side Effects
Sildenafil may have the following side effects:
Pain
Flushing
Dyspepsia
Blurred vision
Photophobia
Chromatopsia
Cyanopsia
Eye irritation, pain and redness
Vertigo
Sleeplessness
Anxiety
Vertigo
Epistaxis
Nasal congestion
Pyrexia
Diarrhea
Vomiting
Priapism
Skin rashes
Erythema
Alopecia
Limb / back pain
Myalgia
Face edema
Fluid retention
Paraesthesia
Urinary tract infection
Dyspnoea
Cough
Fever
Sinusitis
Bronchitis
Cellulite
Sudden deterioration or loss of hearing
Anemia
Leukopenia
Gynecomastia
Frequency of urination or incontinence
Haematuria
Seizure
Cerebrovascular haemorrhage
Transient ischemic attack
Palpitations
Syncope
Hypertension
Hypotension
Hypersensitivity reactions
NAION causes permanent vision loss
Retinal hemorrhage
Potentially Fatal:
Myocardial infarction
Arrhythmia
Tachycardia
Unstable angina
Warning
Do not take Sildenafil with the following drugs:
Alpha-blockers
Cimetidine
Delavirdine
Erythromycin
Itraconazole
Ketoconazole
HIV protease inhibitors
Rifampicin
Bosentan
Potentially Fatal:
Nitrate
Nicorandil
Always tell your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicine, supplements and medicines that you buy without a prescription.
This list does not include all drugs that can interact with sildenafil.
How Does It Work?
Sildenafil is a potent and selective inhibitor of the specific enzyme cyclic guanosine monophosphate (cGMP) phosphodiesterase type 5 (PDE5) in the corpus cavernosum, resulting in relaxation of pulmonary vascular smooth muscle cells. By increasing blood flow to the penis, it restores impaired erectile function; therefore, sexual stimulation is necessary for Sildenafil to achieve its pharmacological effects.
Use
Sildenafil is used to treat the following conditions:
Erectile dysfunction
Pulmonary arterial hypertension
Special precautions and associated warnings
Take special precautions if you have the following conditions:
Patient with anatomical deformation of the penis
Hematological disorders that may predispose to priapism
Not indicated for pulmonary hypertension secondary to sickle cell anemia
Mild to moderate hepatic impairment and severe renal impairment
Children (chronic use)
Pregnancy
Breastfeeding
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